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    Claudin-2 (8H11) Mouse mAb
    EM1403
    規格: 價格:
    50 μl ¥1280.00
    100 μl ¥1980.00

    Overview

    Product name: Claudin-2 (8H11) Mouse mAb
    Reactivity: Human, Rat, Mouse
    Alternative Names: N/A
    Source: Mouse
    Applications : WB, IHC
    Species: Human
    Recommended dilutions: WB 1:1,000-2,000?? IHC:1;100-1:200
    Immunogen: Synthetic Peptide
    Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
    Clonality: Monoclonal
    Isotype: IgG1
    Concentration: 1mg/ml
    Observed band: 25kDa
    GeneID(Human): 9075
    Cellular localization: Cell junction,tight junction,Cell membrane
    Background: The claudin family is composed of 23 integral membrane proteins, and their expression, which varies among tissue types, may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney, where it regulates transepithelial ion (e.g., Na+, Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines , including A549 lung adenocarcinoma cells, where its nuclear distribution was positively associated with enhanced proliferation .
    朋友娇妻的滋味中文字幕