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      COX-2 (2G1) Mouse mAb
      EM1339
      規格: 價格:
      50 μl ¥1280.00
      100 μl ¥1980.00

      Overview

      Product name: COX-2 (2G1) Mouse mAb
      Reactivity: Human, Mouse, Rat
      Alternative Names: PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody
      Source: Mouse
      Applications : IHC
      Species: Human
      Recommended dilutions: IHC 1:100-200
      Immunogen: Synthetic Peptide
      Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
      Clonality: Monoclonal
      Isotype: IgG1
      Concentration: 1mg/ml
      Observed band: 70kDa
      GeneID(Human): 5743
      Cellular localization: Endoplasmic reticulum,?Membrane,?Microsome
      Background: Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
      国产69精品久久久久久妇女迅雷