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    phospho-MLKL (S358) (6B4) Mouse mAb
    EM1320
    規格: 價格:
    50 μl ¥1280.00
    100 μl ¥1980.00

    Overview

    Product name: phospho-MLKL (S358) (6B4) Mouse mAb
    Reactivity: Human
    Alternative Names: Mixed lineage kinase domain like protein, FLJ34389
    Source: Mouse
    Applications : IHC
    Species: Human
    Recommended dilutions: ?IHC 1:100-200
    Immunogen: Synthetic Peptide
    Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
    Clonality: Monoclonal
    Isotype: IgG1
    Concentration: 1mg/ml
    Observed band: 54kDa
    GeneID(Human): 197259
    Cellular localization: Cell membrane,?Cytoplasm,?Membrane
    Background: Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
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