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    CK19 Mouse mAb
    EM1051
    規格: 價格:
    50 μl ¥1280.00
    100 μl ¥1980.00

    Overview

    Product name: CK19 Mouse mAb
    Human Swiss-Prot No.: P08727
    Reactivity: Human, Rat, Mouse
    Alternative Names: Cytokeratin 19, K19, K1CS, keratin 19, KRT19
    Source: Mouse
    Applications : IHC
    Species reactivity: Human, Rat, Mouse
    Species: Human
    Recommended dilutions: IHC 1:200
    Immunogen: Synthetic Peptide
    Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
    Clonality: Monoclonal
    Isotype: IgG1
    Concentration: 1mg/ml
    Observed band: 44kDa
    GeneID(Human): 3880
    Cellular localization: Cytoskeleton,Cytosol
    Background: This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
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