||ZnT-8 Rabbit pAb
||SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
||Synthesized peptide derived from the Internal region of human ZnT-8. at AA rangle； 140-220
||PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
||Zinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.